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Structure-based design of drugs targeting the polymerases of HIV and flu: overcoming resistance via strategic flexibility

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Synopsis: This talk will focus on structure-guided optimization of anti-HIV and anti-influenza inhibitors using synthetic medicinal chemistry, crystallography, biochemistry, and molecular modeling.
Start Time: Wednesday, February 5, 2014 12:00 PM
End Time: Wednesday, February 5, 2014
Location: Center For Integrative Proteomics Research(Cipr)
Address: 174 Frelinghuysen Road
Campus: Busch
Room: 120
City, State, Country: Piscatway, NJ US
Fee: N/A
Speaker: Eddy Arnold, Rutgers University
Sponsor: Proteomics/BioMaPS
Category: Talk, Lecture, Seminar
Web Site: http://proteomics.rutgers.edu/public/?q=content/upcoming-seminars
Contact Name: Maria Voigt
Contact Email: maria@rcsb.rutgers.edu
Contact Phone: (848) 445-4987
Additional Information: The development of two widely used anti-HIV drugs and an inhibitor showing effective anti-flu activity in cell culture will be discussed.
In celebration of 2014: International Year of Crystallography