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“IGFBP-3 mediates intrinsic apoptosis through modulation of NFκB signaling and Bcl-2 family proteins”

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Synopsis: IGFBP-3 mediates the ability of ribotoxins to induce intrinsic apoptosis in mammary epithelial cells. The goal of this work was to delineate the underlying mechanisms for this effect with emphasis on the Bcl-2 family of proteins and the pro-survival NF-kB signaling pathway.
Start Time: Friday, April 7, 2017 9:15 AM
End Time: Friday, April 7, 2017 10:30 AM
Location: Foran Hall
Address: 59 Dudley Road
Campus: George H. Cook
Room: 138A
City, State, Country: New Brunswick, NJ US
Fee: N/A
Speaker: Jennifer Hanke
Sponsor: Animal Sciences
Category: Talk, Lecture, Seminar
Contact Name: Wendie Cohick, Ph.D.
Contact Email: cohick@rutgers.edu
Contact Phone: (848) 932-6319